RNA Details
Disease Name
skin fibrosis
Tissue
skin
RNA Symbol
miR-9-5p
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
immunofluorescence etc.
Target
NA
Pathway
NA
PubMed ID
Title
Protective role for miR-9-5p in the fibrogenic transformation of human dermal fibroblasts
Year
2016
Function
Mir-9-5p significantly prevents fibrogenesis in skin fibrosis. This is mediated by an abrogation of tgf-beta-mediated signaling through the down-regulation of tgfbr2 expression in hdfs. These results may pave the way for future diagnostic or therapeutic developments for skin fibrosis based on mir-9-5p.